Diabetic ketoacidosis

16th july 2023

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Patient came to casualty with

C/O:1) Shortness of breath since afternoon

        2)Fever since afternoon

        3)Rash over the abdomen since 3 days


HOPI:

Patient was apparently asymptomatic 2 hours ago then she developed SOB, sudden in onset, grade - 4. No orthopnea and PND.

No H/O chest pain, Pedal edema, palpitations, excessive sweating, giddiness and wheeze

Fever since 8 hours, high grade, a/w chills and rigor since 2 pm afternoon

Rash over the abdomen since 3 days, no itching or redness, watery discharge. Applied crushed paracetamol tablet on the rash



No H/O , loose stools, pain abdomen, giddiness. 


Dialy routine of patient : 

Wakes up at 6 am in the morning 

Takes insulin at 7:15 am( 4 units of isophane and 6 units of HAI) and eats breakfast at 7:40 am

Starts to school at 7:50 am (travels via grandfather's bike) 

Has Lunch at 12:30 pm

Comes home at 5 pm and eats snacks

Goes to tution from 5 - 8 pm

Takes insulin at 8:15 pm (4 units of isophane and 6 units of HAI) and eats at around 8:40 pm 

Sleeps at around 10 pm

Events on 13-07-23 : 

Woke up at 7 am 

Missed the morning dose of insulin and breakfast because she was late to school 

Went to school at 8 am 

Felt giddiness and told the  Teacher about it. Teacher asked her to eat. 

Refused to eat due to nausea 

Had Vomiting at 11 pm - water content 

At 12:30 vomited once again - water content 

Informed her grandfather and went home at 1 pm

At home she started developing SOB so didn't eat again

Went to local doctor due to SOB  at 5 pm

She was put on O2 there and when it didn't resolve the doctor advice to go to higher centre 

Came to kamineni at 7:30 pm 

Past history :

Patient is known case of Type 1 DM since 3 yrs.

 Diagnosed 3 yrs before when she complained of polyuria.

After diagnosis she used to take 4+4 HAI and Isophane in the morning and night. And 2+2 HAI and isophane in the afternoon. 

After one year, on a regular checkup, her sugars weren't controlled, So she was advice to take  HAI - 6 IU, Isophane - 4 IU 20 mins before eating since 2 years . 

 H/O right humerus fracture 1 year back (skid and fall from bike while going to school). Treated conservatively with cast for 1 month 

Family history : H/O Type 1 DM in father. Diagnosed at 12 years. Was on insulin treatment. 

Father was on dialysis due to CKD 7 yrs back and died 5 years back

General examination : 

No signs of pallor, icterus, cyanosis, clubbing, Lymphadenopathy and pedal edema 



Vitals on admission : 

PR : 158 bpm 

BP : 110/60 mmhg 

TEMPERATURE : 98.6 F

RR : 54 cpm

Spo2 : 98% on RA

GRBS : High 





Systemic examination :

RESPIRATORY SYSTEM EXAMINATION : 

Bilateral air entry +

Normal vesicular breath sounds 

Trachea central 

No added sounds 


CVS EXAMINATION : 

S1, S2 heard 

No murmurs 


ABDOMEN EXAMINATION : 

No tenderness 

No organomegaly

Bowel sounds - present 

Rash on the abdomen 





CNS EXAMINATION : 

Gcs - E4V5M6 (15/15)

Higher mental functions - normal 

Cranial nerve examination - normal 

Sensory and motor system normal 

No signs of meningeal irritation


Investigations :


URINE FOR KETONE BODIES : positive 


RANDOM BLOOD SUGAR : 624 mg/dl 

HEMOGRAM : 




RFT: 


LFT :



CUE:




Diagnosis : Diabetic ketoacidosis with type 1 DM


Treatment : 

1) IV fluids 40 ml bolus followed by NS 150 ml/hr 

2)INJ HAI - 8 IU / stat 

3)Inj HAI 40 IU in 39 ml NS @ 6 ml / hr (Inc/Dec according to GRBS) 

4)IV fluids - 5D @ 50 ml/hr if GRBS < 200 mg / dl 

5)Input / Output charting

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